I don't even have floor liners, just the factory mats. I brush the crevices and vacuum the interior after a trip. And take a damp microfiber to all the surfaces I can reach. Its not perfect, but 90% of the interior is plastic and dirt will clean right off if you can reach it. Dust is another issue. Mud dries on carpet and then its dirt which can be broken and vacuumed out. Seats seem to be fine but I also haven't sat in the mud yet. I get in them sweaty and soaking wet sometimes. I have used a leather spray cleaner/conditioner once in the year I have had the truck. Aside from seat covers and floor liners, you could basically do your best to keep the windows up.
2016 Laser Blue Ext Cab Short Bed 4x4 Z71
Fox 2.0 suspension, LineX; custom HiLift, shovel/axe mounts, Chassis Unlimited rock sliders, LED hood pods, Custom aluminum oil pan and transmission skid plates, custom bed cage, MBRP cat back, lots of scratches.